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Hearing Loss and Antiretroviral Therapy in Patients Infected with HIV-1
Arch Neurol 54:407-410, Marra,C.M.,et al, 1997
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Article Abstract
Hearing loss was common,seen in 29 subjects(29%).It was significantly associated with age and history of ear infection and tended to be more common in subjects prescribed antiretroviral agents.An interaction existed between age and antiretroviral therapy;the association between hearing loss and antiretroviral therapy was significant for subjects aged 35 years or older,but not for subjects younger than 35 years.In subjects aged 35 years or older,the association remained significant using a multivariate model that included those variables found to have the greatest potential for confounding(odds ration,4.6;95%confidence interval,1.0-20.5;P=.-5). Hearing loss is common among HIV-infected individuals and is associated with antiretroviral therapy in those aged 35 years or older.
 
Related Tags
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adverse drug reaction
antiviral agents
hearing loss
human immunodeficiency virus type 1
ototoxicity
treatment of neurologic disorder

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